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Trimethylamine N-Oxide (TMAO) Impairs Purinergic Induced Intracellular Calcium Increase and Nitric Oxide Release in Endothelial Cells
And injection comfort decreases at higher doses
Quick Answer: Neither is objectively "better" because they serve different functions
Nat Rev Neurosci 8:171181
The verdict: which one should you choose After examining every angle of this comparison, the data points in one direction for most people
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