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Dit medicijn bootst kunstmatig twee hormonen na die van nature in de darmen vrijkomen na het eten: Glucagonachtig peptide-1 (GLP-1) en Glucoseafhankelijk insulinotropisch polypeptide (GIP)
It works by delivering propionate directly to receptors in the colon, which trigger appetite-regulating hormones
Two phase II trials - one in a population with obesity (without T2D) [45], and a second in a population with T2D and overweight/obesity [46], have recently been published and their key findings are presented below (Table 1)
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