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HR representatives from several of the large firms also discussed why use of GLP-1 agonists may increase, despite the large cost burden that they have placed on benefit spending

Other documented findings include a tendency toward IGF-1 receptor desensitization with prolonged, continuous exposure, transient fluid retention in early study phases, and at supraphysiological exposure levels examined in some research acromegaly-like tissue changes

For current customers, those decisions will be made with the renewal of their health plan, the statement said

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