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Journal of European Academy of Dermatology and Venereology
Your genetic profile matters here too: if your FTO rs9939609 variant indicates higher genetic predisposition to weight regain, consistent dosing (whether morning or night) and reliable appetite control from tirzepatide becomes especially important for long-term success
Planning your dose increases around your social calendar, while not always practical, can help you manage the most intense days
Aim for 64+ oz daily, taken in small sips throughout the day
Important caveat: This was a retrospective study, so causality cannot be confirmed
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