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FIGURE 2 3 Redox dysregulation in disease states 3.1 GSH in peripheral immune cell infiltration Several studies indicate that neuroinflammatory changes associated with neurodegeneration compromise the BBB or its function by disrupting transport systems, facilitating the infiltration of immune cells, and influencing the BBBs role as a signaling interface

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In reporter and cell assays, SLU-PP-332 is active at sub- to low-micromolar concentrations

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Generally, roGFP probes are appropriate for measuring the thiol/disulfide equilibrium within a linear range of about 30 mV from their midpoint potential equivalent to an OxD between 10 and 90%

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