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However, as GLP-1R expression is generally absent in most tumor specimens, the anticancer effects of Ex-4 may be restricted to specific patients with ovarian cancer who also have diabetes [72]

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Here is what each group received: 1mg group: 1mg weekly for the full 48 weeks, no escalation 4mg (starting at 2mg): Started at 2mg, escalated to 4mg after 4 weeks 4mg (starting at 4mg): Started directly at 4mg, no escalation 8mg (starting at 2mg): Started at 2mg, escalated through 4mg to reach 8mg 8mg (starting at 4mg): Started at 4mg, escalated to 8mg after 4 weeks 12mg (starting at 2mg): Started at 2mg, escalated through 4mg, 8mg to reach 12mg The weight loss results at 48 weeks told a clear story

Thyroid Cancer Risk : There has been concern about a potential link between GLP-1 receptor agonists and the development of thyroid cancer

Davies MJ, Deanfield JE, Frias JP, et al