Tesamorelin produces a pulsatile, physiologically normal GH release
Although the primary metabolic abnormalities leading to fat accumulation in hepatocytes remain to be elucidated, they include alterations in the pathways involving lipid uptake [dietary chylomicron remnants or adipose tissue-derived free fatty acids (FFAs)], synthesis (lipogenesis), degradation (lipolysis and lipophagy), or secretion of hepatic lipoproteins (e.g., very low-density lipoprotein [VLDL])
And I would expect that the clinical necessity of that will be really clear with these medications as people know, there are real side effects
Most of what we know comes from patient reports, observational studies, and reasoning from the physiology of weight loss
Consult a healthcare professional to determine the best treatment option It is crucial to consult a healthcare professional to determine the most suitable treatment option based on individual needs and medical history