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The practical consequence of this mechanism is that BPC-157 works best when it can physically reach the target tissue
In naturally aged mice and in doxorubicin-treated mice, FOXO4-DRI treatment significantly improved physical fitness, restored fur density, improved renal function, and improved liver function effects attributed to the selective elimination of accumulated senescent cells
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Monitoring strategies include periodic assessment of treatment response, adjustment of protocols based on outcomes, and long-term maintenance planning
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