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Although MRI offers superior lesion detection, its use is limited by moderate specificity, higher cost, and increased likelihood of false-positive findings, which necessitate careful clinical correlation

Most adverse effects are associated with improper dosing and excessive intake

In cell-culture studies, gene-expression and protein-synthesis changes are described over hours to a few days

The TRIUMPH program includes multiple phase 3 trials, and one trial, TRIUMPH-Outcomes, is specifically designed to answer the question of whether retatrutide reduces major adverse cardiovascular events