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The side effect profile stays mild because ipamorelin targets growth hormone release without disturbing cortisol, prolactin, or appetite regulation

Some may notice brighter-looking skin after a few sessions, while others may require a longer period depending on their baseline skin condition and individual response

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While many people feel their skin is more soothed and hydrated right away, visible improvements in persistent redness and irritation typically become noticeable after 4-6 weeks of consistent daily use