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Pharmacokinetic and pharmacodynamic alterations of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors: drug-drug interactions and interindividual differences in transporter and metabolic enzyme functions
The population with obesity showed similar prevalence rates, with 33.7% for NASH and 75.3% for NAFLD
Hydrodynamic diameter and zeta potential values of prepared PLGA nanoparticles were measured using Zetasizer Nano-ZS (Malvern instruments, UK)
Many studies have investigated the interactions between antioxidants and enzymes in CVDs
This suggests that some therapeutic benefits of canagliflozin could result from the activation of AMPK, rather than inhibition of SGLT2 (Hawley et al., 2016)
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