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While Novo Nordisk and rival obesity therapy manufacturer Eli Lilly are starting to overcome the production constraints that coupled with massive demand have resulted in shortages, Noom's WSJ ad calls for US policymakers to keep the status in place "until GLP-1s cost the same in NYC and London." The FDA has received adverse event reports involving patients who have used them and has taken action against some compounders making versions available based on salt forms of the drug that are unapproved, including semaglutide sodium and semaglutide acetate, so the availability of compounded forms has become controversial

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When a branded drug is on a shortage list, or if patients cannot afford the high out-of-pocket costs, some may turn to online or compounding pharmacies for alternatives

In this article, Ill give a quick background on Medicares long-standing exclusion of weight-loss medications, explain the BALANCE and Bridge models, and break down what this means for patients, physicians, and the health system