Many patients using GLP-1 therapy report better endurance, improved sleep, steadier energy, and an overall feeling of being more balanced and capable
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Compared to the placebo, the tripeptide infusion reduced mean daily food intake by 27%, decreased fat intake, increased protein intake, and enhanced satiety, while not altering food preferences and sweet taste function
The table below shows how often specific reactions were reported in each drugs FDA approval trials
First, we emulated the two cardiovascular outcome trials SUSTAIN-6 (semaglutide versus placebo) and SURPASS-CVOT (tirzepatide versus dulaglutide) using the RCT-DUPLICATE approach to benchmark findings and inform the study design and analytic approach for expanded questions