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Usually resolves by adjusting timing or having a small meal sooner

Injections bypass the digestive tract and, as a result, the vitamin B12 has a more direct route to the cells and can be more readily metabolised

NICE Clinical Knowledge Summaries recommend B12 injections for: Pernicious anaemia an autoimmune condition affecting intrinsic factor production Malabsorption syndromes including coeliac disease and inflammatory bowel disease Post-surgical states particularly following gastrectomy or ileal resection Strict vegan diets when oral supplementation proves inadequate, though oral cyanocobalamin is usually sufficient for dietary deficiency Clinical trials demonstrate that B12 injections rapidly improve haematological parameters and neurological symptoms when deficiency is confirmed through blood tests

Primary (testicular failure) hypogonadism responds only

Goldstein et al