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The most frequently reported adverse events with combination therapy are gastrointestinal symptoms, including nausea, vomiting, and diarrhea, which are primarily attributable to GLP-1 receptor agonists and may occur more often than with SGLT2 inhibitor monotherapy [24, 43]
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Gene-Expression Readouts: Research reports changes in gene sets linked to remodeling, inflammation signaling, and oxidative defense
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