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doi:10.1038/379069a0 23
Results of repeated measures linear mixed effect models indicated a significant interaction between group and time for BrAC ( 2 (7) = 16.36, p = 0.022, f = 0.36)
There was more hypoglycemia and weight gain (+1.1 kg) in the glipizide group, whereas the sitagliptin group had weight loss (-1.5 kg)
This success led to the development of exenatide, the first GLP-1 receptor agonist approved by the FDA for the treatment of diabetes (in 2004)
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