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Novel action of paclitaxel against cancer cells: bystander effect mediated by reactive oxygen species

Ethanol metabolism, CYP2E1 induction, compromised antioxidant defenses, mitochondrial injury, activation of Kupffer and stellate cells, hypoxia, and iron overload can all contribute to the alcohol-induced oxidative environment

Silva FM, Kramer CK, de Almeida JC, Steemburgo T, Gross JL, Azevedo MJ

But when bombarded with toxins and free-radical damage from the sun, pollution, poor nutrition, or chronic stress, our bodies cant keep up

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