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Description

So, semaglutide dosing and titration may step back when gaps happen

This is not unusual and reflects the complex interplay of slowed gastric emptying (which promotes constipation) and altered intestinal motility (which can trigger diarrhea)

GLP-1 medications deliver substantially greater weight loss: semaglutide trials showed 1015% body weight reduction over 68 weeks, and tirzepatide (a dual GLP-1/GIP agonist) demonstrated 20%+ reductions in some cohorts