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FDA has already approved this IDH1 inhibitor for patients with refractory acute myeloid leukemia (AML) who have IDH1 mutation(s) as a candidate drug to be tested in combination with bipolar antiandrogen therapy [45]
Wang H, Yin W, Ma S, Wang P, Zhang L, Li P, et al
Cycling further minimizes accumulation
RABL6A Is an essential driver of MPNSTs that negatively regulates the RB1 pathway and sensitizes tumor cells to CDK4/6 inhibitors
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