Getting into the mitochondria can prove to be quite tricky, but once inside, fatty acids can be oxidized very readily
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10.1007/s00216-006-0980-6 Li Y, Hugenholtz J, Sybesma W, Abee T, Molenaar D: Using Lactococcus lactis for glutathione overproduction
The human body is capable of producing L-Carnitine, but not in sufficient quantities to meet the bodys needs