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According to Supriya Rao, MD, gastroenterologist, director of medical weight loss at Lowell General Hospital, and clinical assistant professor at Tufts University School of Medicine, you can take your medication a few hours earlier or later than usual on your regular dosing day without risking any side effects or interfering with the therapeutic benefits of the drug

Semaglutide primarily targets the GLP-1 receptor

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However, if aches worsen or remain severe despite conservative measures, a dose adjustment or medication switch may be necessary