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Only a small, yet significant amount is metabolised via the hepatic cytochrome P450 enzyme system (its CYP2E1 and CYP1A2 isoenzymes), which is responsible for the toxic effects of paracetamol due to a minor alkylating metabolite (N-acetyl-p-benzo-quinone imine, abbreviated as NAPQI).[17] There is a great deal of polymorphism in the P450 gene, and genetic polymorphisms in CYP2D6 have been studied extensively
General Chemical Properties COA BPC-157 interacts with cellular signaling pathways to modulate growth factors, cytokines, and extracellular matrix components
The protocol was approved by the Committee on the Ethics of Animal Experiments of Fudan University
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