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GCLC-KO mice showed activation of C1q, which triggers engulfment of neurons by microglia, and disease-associated-microglia (DAM), suggesting that activation of microglia is linked to the neuronal loss

The underlying mechanisms by which tesofensine exerts its cognitive benefits are not fully understood but may involve modulation of neurotransmitters and neurotrophic factors involved in brain function and plasticity

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And it turns out that there was no way the vested interests were going to allow that to happen

The Achilles that flares every time you try to run again