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From weight regain to returning hunger and blood sugar changes, here is a science-backed breakdown of what patients can expect when they stop taking a GLP-1 medication
Plain water alone can make things feel worse
When appetite drops too low, protein intake often declines as well, which can impact energy, metabolism, and muscle maintenance
Signs that you may be ready to increase your dose Your provider will typically consider a dose increase when: You have been on your current dose for at least 4 weeks with no significant side effects Nausea, vomiting, or stomach discomfort from the previous dose increase has resolved Your weight loss has plateaued at the current dose, and you have not yet reached your goal Your blood sugar levels (if you have diabetes) are not yet in your target range Signs you are not ready to increase Your provider will typically delay a dose increase if: You are still experiencing nausea, vomiting, diarrhea, or stomach pain from your current dose You have missed doses recently due to side effects You have experienced any serious adverse event at the current dose that has not fully resolved Do you need to reach 15 mg
Interest stems mainly from their metabolic and weight-management effects, but robust human clinical trial evidence supporting direct thyroid or autoimmune benefits is lacking
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