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Due to the particular metabolic characteristics of these cells, only the two first reactions of the pentose via (also called hexose monophosphate) have the capacity to generate NADPH + H
In short, it uses body fat as fuel
Hobbs et al., 2000) have suggested that polymorphisms of genes encoding enzymes involved in the folate metabolic pathway, also known as one-carbon metabolism, may be maternal risk factors for the birth of a child with Down syndrome (DS)
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