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Pregnancy Pregnancy Category C Adequate and well-controlled studies have not been done in pregnant women
In contrast, GCLC inhibition exerted a minimal impact on the growth of PDX tumors with low ACTL6A expression (cases 2 and 4) tumors (Fig
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Consequently, this leads to a loss of skin color in the affected regions, resulting in conspicuous pale spots ranging in size from a few millimeters to several centimeters (169)
However, results plateaued after week 10, suggesting receptor saturation or limited penetration
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