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Further according to Professor Khavinson, epithalamin augments the in vitro outgrowth of explants from the pineal gland but not from other tissues and has been found to offer the following anti-aging and longevity benefits [6, 7]: Increases melatonin production in rat pineal glands Improves immunological parameters in animals (rats and mice) Exhibits anticarcinogenic effects in various experimental models Stimulates antioxidant defenses Restores reproductive function in old rats There is clear evidence from clinical trials that the peptide increases the lifespan of animals (namely rats, mice, and fruit flies), and exhibits geroprotective activity in humans

Since vitamin B12 absorption relies on adequate stomach acid to release it from food, long-term use of these medications may put you at increased risk of deficiency

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[8] Mller TD, et al