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Skin elasticity using a cutometer was measured at baseline, at 4 weeks, and then 4 weeks after discontinuation of the treatment, which showed significant improvement in skin elasticity, even in sun-exposed skin areas, during these time points compared with baseline values [39]
It acts as a non-selective agonist at MC1R, MC3R, MC4R, and MC5R, with particularly high potency at MC1R, the receptor governing melanogenesis in epidermal melanocytes via the cAMP-PKA-MITF pathway
PMCID: PMC10239052
Changes in body composition, energy levels, and muscle tone typically require 8-12 weeks of consistent use, though individual response varies based on dosing, lifestyle, and baseline growth hormone levels
As one of the primary bioactive constituents found in plants, natural plant polysaccharides exhibit a broad spectrum of biological activities
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