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In vitro pharmacology (EC 50 ) Evaluation of the agonist activity of compounds 1 23 at the mouse GLP-1 receptor endogenously expressed in TC6 cells, was determined by measuring their effects on cAMP production using the HTRF detection method (performed by Cerep S.A., catalogue 2015, ref
The targets are the GLP-1 receptor (glucagon-like peptide-1), the GIP receptor (glucose-dependent insulinotropic polypeptide), and the glucagon receptor
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The custom code used to analyze the fiber photometry data in this paper is archived at Supplementary Materials The PDF file includes: Download 6.89 MB Other Supplementary Material for this manuscript includes the following: Download 138.64 KB REFERENCES AND NOTES Cureus 14 , e22090 (2022)
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