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This is particularly important when switching from a GLP-1 based therapy to non-GLP-1 options, because the metabolic adjustment can affect blood sugar regulation, blood pressure, and heart rate in ways that warrant monitoring
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Synthetic mRNAs, which transiently express functional cystinosin, have demonstrated beneficial and sustained impacts on proximal tubular resorptive function, proteinuria, and kidney morphology in zebrafish after treatment [157]
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