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What to Expect with Semaglutide Treatment Initial treatment begins with the smallest effective dose of semaglutide, which is increased as tolerability and effectiveness are assessed

Your provider may need to: Reduce your insulin dose when starting a new, potentially more potent GLP-1 drug Increase monitoring frequency (more frequent blood sugar checks) Adjust sulfonylurea dosing to prevent dangerous lows Blood Sugar Expectations There may be a brief period during the transition where blood sugar control is slightly less tight particularly if you're moving from a higher dose of one drug to the starting dose of another

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Furthermore, integrating lifestyle changes such as: A balanced diet Regular exercise Proper hydration can enhance the medications effectiveness