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As put by the authors of a 2019 review on drug-phospholipid complexes, the combined affinity for fats and water means that phospholipids function as emulsifiers that enhance absorption and, therefore, bioavailability.4 Indeed, a 1990 human study found that a silymarin-phospholipid complex resulted in plasma levels of silybin (silymarin's main active component) that were more than double the amount provided by an equal quantity of pure silymarin 298ng/mL versus 102ng/mL per 120mg of silybin.34 Given the science behind phospholipid-based drug delivery, we can conclude that Life Extension is likely capable of delivering more per-dose silymarin, as well as isolated silybin, than either NOW or HUM (neither of which uses phospholipids)

Collaborating with healthcare professionals ensures a tailored approach to supplementation, optimizing individual health needs and enhancing treatment outcomes

When available, COA or batch documentation should be referenced for identity and quality review before use in any research workflow

When considering supplements, it's important to consult with a healthcare provider to determine the most effective form based on individual health needs and goals

GHK, a tiny peptide often bound to copper