tirzepatide brain reduces food intake and appetite, and affects functioning, more than placebo and liraglutide A new study provides the

The broader lesson from the oral secretagogue MK-677, which raised IGF-1 durably yet did not translate into unambiguous functional gains in key trials, is a cautionary reference point for the whole class

Alberta Blue Cross's 2026 drug pipeline report says glucagon-like peptide-1 therapies remain a major cost driver for private drug plans in Canada, with future expanded uses potentially including metabolic dysfunction-associated steatohepatitis (MASH) and obstructive sleep apnea (OSA)

These results led to FDA approval of semaglutide 2.4 mg (Wegovy) for long-term weight management in adults with overweight or obesity

You need to permanently move your injection day

Rather than pushing through at a dose that makes daily life miserable, stepping back to a lower dose or splitting doses across the week can maintain progress while reducing side effect burden