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If you are uncertain about any aspect of an authorised retatrutide protocol, always seek advice from the trial team, a registered pharmacist, GP, or specialist clinician before proceeding

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For the highest dose group (12 mg), this is what the titration schedule looked like: Weeks 1-4 : 2 mg once weekly Weeks 5-8 : 4 mg once weekly Weeks 9-12 : 8 mg once weekly Weeks 13 onward : 12 mg once weekly What phase 3 trials show so far: Testing long-term dosing of retatrutide In more recent phase 3 trials , the doses used are a bit different, but the overall structure still follows that same gradual, step-by-step pattern

[1] [4] Additionally, Ozempic is indicated to reduce the risk of major adverse cardiovascular events (cardiovascular death, non-fatal myocardial infarction, or non-fatal stroke) in adults with type 2 diabetes and established cardiovascular disease

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