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Other medicines warranting caution include: Oral contraceptives the tirzepatide SmPC (Mounjaro, MHRA/emc) notes a reduction in oral contraceptive exposure during initiation and dose escalation, and advises considering additional contraceptive precautions during this period

GLP-1 class medications carry a known cautionary flag here

A glucagon receptor agonist can help the body burn more energy

J Nutr 135:17181725

This is the perfect place to ask, "Is this side effect normal?" or "Should I adjust my dose?" Dose Adjustments: If side effects are bothersome, your provider might suggest delaying a dose increase or adjusting your titration schedule to give your body more time to adapt