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It is precisely this unique distribution that enables AQP4 to precisely regulate the transport of water molecules across the BBB, thereby maintaining water and electrolyte balance in the CNS (53)

All authors contributed to final edits of the manuscript

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Metformin Suppresses Systemic Autoimmunity in Roquin(san/san) mice through inhibiting B cell differentiation into plasma cells via regulation of AMPK/mTOR/STAT3