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More importantly, the freezing and thawing process can affect the homogeneity of the solution
Besides death, CLD causes severe damage to patients quality of life, as well as substantial medical and economic costs (Stepanova et al., 2017)
reported that the exosomes present in the CSF of PD patients exhibit -syn aggregate formation
Vitamin B12 is crucial for several physiological processes, including: Red blood cell formation deficiency leads to megaloblastic anaemia, characterised by large, immature red blood cells Neurological function B12 is required for myelin synthesis and nerve health DNA synthesis essential for cell division and growth Without adequate B12, patients may develop symptoms such as fatigue, pallor, shortness of breath, glossitis (sore tongue), paraesthesia (pins and needles), and in severe cases, neurological complications including peripheral neuropathy, ataxia, and cognitive impairment
The narrowing constricts the spinal cord and surrounding nerves, causing pain and other symptoms
