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For people with obesity-related conditions like type 2 diabetes, cardiovascular disease, or sleep apnea, that delay carries medical risk

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Burckbuchler V, Mekhloufi G, Giteau AP, Grossiord JL, Huille S, Agnely F

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Another randomized controlled clinical trial specifically focusing on their weight loss effects demonstrated that, in adults with overweight or obesity without diabetes, once-weekly subcutaneous injection of semaglutide resulted in significantly greater weight loss at 68 weeks compared with once-daily subcutaneous injection of liraglutide, and the incidence of gastrointestinal adverse reactions was similar between the two groups [Reference Rubino, Greenway, Khalid, ONeil, Rosenstock and Srrig47]