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Revolutionary NNMT Inhibition Mechanism 5-Amino-1MQ functions as a potent selective inhibitor of nicotinamide N-methyltransferase with IC = 1M, preventing the enzyme from converting nicotinamide to 1-methylnicotinamide

But for people who have SNPs in methylation-related genes, like MTHFR, they may be unable to efficiently convert cyanocobalamin to usable forms

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