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If gut repair reduces inflammatory signaling originating in the digestive tract, it could potentially improve metabolic regulation and insulin sensitivity

Why Perfect B Is Evaluating AOD 9604: Our Clinical Perspective We began our internal evaluation of AOD 9604 in response to a consistent pattern we were seeing with patients in our South Florida practice: people who had experienced meaningful fat loss on GLP-1 medications, then plateaued or discontinued due to side effects, and were looking for a next option

The treatment group showed significant reductions in body weight (approximately 5% loss) and white adipose tissue mass (35% reduction) compared to control animals, despite no changes in food intake

Glutamate can also be deaminated via glutamate dehydrogenase to regenerate -ketoglutarate and release ammonia, a mechanism well-document in vertebrates for nitrogen and anaplerotic balance 74