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Mult Scler Relat Disord 29:2634
Miklossy, G., Hilliard, T
Destruction of oxidatively-damaged RBCs is accomplished extravascularly by macrophages in the reticuloendothelial system 56
This copper-binding tripeptide activates TGF-beta/SMAD pathway signaling, stimulates collagen I and III synthesis, upregulates TIMP-1 and TIMP-2 to protect collagen from degradation, and modulates gene expression across approximately 4,000 human genes
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