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While relevant research in rodents have successfully encapsulated similar phenomena in clever experimental designs [33], in this domain the differences between rodents and humans are arguably larger than in the case of homoeostatic regulation serving basic survival instincts

For most patients this resolves within a few weeks once the body adapts

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Suppressing the PKCII-ACSL4 pathway mitigates ferroptosis in vitro and obstructs immunotherapy-induced ferroptosis in vivo [16]