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Epitalon has been shown to significantly increase the expression of key antioxidant enzymes: Superoxide dismutase (SOD-1) Catalase NAD(P)H quinone dehydrogenase 1 (NQO1) These effects are mediated via the Keap1/Nrf2 signaling pathway [40, 41]: a master regulator of cellular redox balance
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Caspase-1 is the effector component of the NLRP3 inflammasome and is activated through proximity-induced autocatalytic activation upon recruitment to the NLRP3 inflammasome
95% CI [0.690.90])
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