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The SELECT trial establishing semaglutides 20% reduction in major adverse cardiovascular events has converted GLP-1 receptor agonists from single-indication obesity drugs into foundational chronic disease therapeutics demanding continuous prescription renewal
Emotionally, that can take a toll
What is GLP-1 and why is it used for weight management
It has to be mentioned that KO mice for IGF-1 gene are not viable and studies in such mice have to be done in the first days of life, and thus results are not very conclusive as metabolism is not properly established at this stage [129, 228]
A., Gehrke, S., Hansen, K
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