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doi: 10.1016/j.cld.2016.06.006 5 LocarniniSMasonWS

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Our advice is to speak to your GP about the risks and benefits of GLP-1 medicines before taking them, and only take those prescribed by a healthcare professional. The authors say that further studies evaluating the impact of these medications on pregnancy and unborn babies are warranted

Versus sulphonylureas (such as gliclazide), GLP-1 receptor agonists offer comparable glucose-lowering efficacy but with significantly lower hypoglycaemia risk and the advantage of weight loss rather than weight gain

The process is driven in part by genes in what's known as the "mitochondrial respiratory chain complex," a group of enzymes that help convert oxygen, sugar, and proteins into ATP through a process called oxidative phosphorylation