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Falling short of this target accelerates muscle loss and compounds fatigue through multiple pathways

Roughly 1 in 8 (12%) consumers have taken a GLP-1 drug , per KFF, and that share is likely to rise: 26% of US consumers plan to take a weight loss drug to achieve their 2025 New Year's resolution goals , per Tebra

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For example, butyrate may indirectly regulate -hydroxybutyrylation by enhancing hepatic ketogenesis, generating -hydroxybutyrate as a critical substrate

These factors are important to consider in the quest to enhance antiaging influences and expand the healthspan of humans in the future [9, 16]