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Genetic variants in glucose-dependent insulinotropic polypeptide receptor (GIPR rs1800437), and appetite-regulation genes (FTO rs9939609, MC4R rs17782313) correlate with differential treatment response

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Month 3 onward shifts to protein preservation (80-100g daily), gallbladder protection (30-50g healthy fats), and nutrient density since appetite remains suppressed through week 48

In addition, poor mood and concentration, irritability, depressive symptoms, inability to sleep normally, nausea, vomiting, diarrhea, and even numbness and tingling in your hands and feet can be signs of a Vitamin B12 deficiency