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The body needs fuel, has plenty stored as fat, but cannot access it quickly enough
Theres a lot of hype on the Internets airwaves about the myriad health benefits of cold water immersion in particular, including that it may provide a dopamine shock. This idea has some merit
Trobisch at Synergy
Prolonged synaptic glutamate elevation causes excessive neuronal firing, which raises intracellular calcium levels and has subsequent neurotoxic effects
Many teams also build in a washout period at the end of a study before any follow-up dosing phase, giving the GH axis time to return to baseline and reducing the risk of carryover effects confounding a subsequent phase
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