1st week of semaglutide First Weight Loss: What to Expect – PlexusDx First week on semaglutide 6lb

New Study Evaluated Impact on Chronic Ocular Disease, Including Age-Related Macular Degeneration A retrospective cohort study scheduled for publication in Ophthalmology , the journal of the American Academy of Ophthalmology, investigated whether GLP-1 agonists influence the risk for age-related ocular diseases such as age-related macular degeneration (AMD), cataracts, and glaucoma, in an at-risk population

(One small prospective study of early pregnancy GLP-1 users in a handful of European countries and Israel, published recently in BMJ Open , found no increase in major birth defects or pregnancy loss, when compared with control groups of pregnant women with diabetes and pregnant women who are obese

SGLT2i use is associated with an increased risk of DKA and UTI, but confers several favourable outcomes, notably preservation of renal function, reduced risk of developing heart failure and CKD, and of hospitalisation, despite a higher prevalence of heart failure, hypertension, IHD and CKD at baseline

Side effects & tolerability Both medications share a similar side-effect profile, mostly gastrointestinal: nausea, constipation, diarrhea, and reduced appetite especially when starting or increasing the dose

Genes (Basel) (2019) 10(10):798