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The control HGF without the wash-out step ( black bars 2 ) presented higher indices than the levels of regular control HGF at both HGF doses (also see gray bars 3 with wash-out step)

Oral : administration by mouth Intrathecal : infusion into the fluid surrounding the brain and spinal cord Intra-arterial (IA) : injection into an artery Intraperitoneal (IP) : injection into the abdominal cavity Intravesical : administration directly into the urinary bladder through a catheter Intramuscular : injection into a muscle Topical : application to the skin Subcutaneous : injection under the skin 4 Chemotherapy Dose Optimization Conventional chemotherapy regimens are typically calibrated to deliver the maximum tolerable dose of cytotoxic drugs (Baszkowsky 2012

AOD 9604 is not FDA-approved as a pharmaceutical drug